Severe dry eye disease that is chronic and unresponsive to first and second-line treatments can lead to keratopathy, or damage to the corneal surface.
Amniotic membranes, tissue derived from the inner-layer of the fetal membrane, contains anti-inflammatory and anti-microbial properties that promote corneal healing. A temporary, suture-less graft is applied to the corneal surface- similarly to a contact lens- for 5 to 7 days (until the cornea is returned to a normal state).
The DRy Eye Amniotic Membrane (DREAM) study concluded the use of amniotic membranes to be promising to enhance the recovery of ocular surface health and reduce signs and symptoms in patients with moderate-to-severe dry eye disease. There were no adverse events reported, apart from mild discomfort experienced during the placement of the membrane.
This treatment can be utilized on dry eye patients suffering from corneal erosions or neuropathic pain, as well as prior to refractive/cataract surgery to yield the best post-surgical results.
If you have been tirelessly treating dry eye to no avail, you may be an amniotic membrane candidate. Let’s find out!
Aamena S. Kazmi, OD
The Dry Eye Doctor at BFEC
Check out Just Add Water? A Dry Eye Series by the Dry Eye Doctor.